Liquid Chromatography-Mass Spectrometry Systems

Applications: Biopharmaceutical analysis, clinical research, proteomics, metabolomics, natural products

LC-MS/MS Triple Quadrupole Systems

  • Sensitivity: Low femtogram (fg) to picogram (pg) level detection
    Quantitative Performance: Linear dynamic range up to 6–7 orders of magnitude
    SADC Applications:
    Therapeutic drug monitoring (TDM), pesticide residue analysis in food and water, veterinary drug testing, pharmaceutical bioequivalence studies, forensic toxicology
  • Key Benefits:
    Exceptional sensitivity and selectivity using Multiple Reaction Monitoring (MRM), gold-standard quantitative accuracy, robust performance for regulated and high-throughput laboratories
  • Featured Systems:
    Agilent 6470 Triple Quadrupole LC/MS, Thermo Scientific TSQ Fortis, Waters Xevo TQ-XS, SCIEX Triple Quad 7500+

Q-TOF (Quadrupole Time-of-Flight) Systems

  • Resolution: 40,000 to 100,000 FWHM
  • Mass Accuracy: <1 ppm with internal calibration
  • SADC Applications: Natural product discovery (African medicinal plants), wine authenticity testing, sports doping control
  • Key Benefits: High throughput screening, structure elucidation, large molecule analysis
  • Featured Systems: Agilent 6546 LC/Q-TOF, Waters Xevo G3 QTof, SCIEX X500R QTOF

Orbitrap-Based Systems

  • Resolution: Up to 1,000,000 FWHM
  • Mass Accuracy: <1 ppm (RMS) with external calibration
  • SADC Applications: Proteomics research (infectious diseases), lipidomics, biotherapeutic characterization
  • Key Benefits: Unmatched resolution, compatibility with multiple fragmentation techniques
  • Featured Systems: Thermo Scientific Orbitrap Exploris 240, Orbitrap Eclipse Tribrid

Ion Trap Systems

  • Ideal For: Method development, teaching laboratories, MSⁿ capabilities
  • SADC Applications: Small molecule structural elucidation, reaction monitoring
  • Key Benefits: Cost-effective MS/MS, easy operation, compact footprint
  • Featured Systems: Bruker amaZon SL, Thermo Scientific LTQ XL

LC-MS Solutions for African Laboratories:

  • Climate-Adapted Systems: Designed for variable power quality and temperature conditions
  • Local Method Libraries: Pre-validated methods for common African matrices
  • Training Programs: Hands-on workshops in Johannesburg, Cape Town, and Dar es Salaam
  • Consumables Supply: Local stock of LC-MS columns and accessories

Request a Free Consultation

Whether you require equipment, technical support, or strategic scientific consultancy, our team is ready to assist.