Liquid Chromatography Systems (HPLC & UHPLC)
Chemplanet supplies a comprehensive range of Liquid Chromatography (HPLC and UHPLC) systems designed to deliver high-resolution separations, excellent sensitivity, and long-term reproducibility. Our solutions support laboratories operating in quality control, research & development, biopharmaceutical analysis, and environmental testing.
Analytical HPLC & UHPLC Systems
(QC, Research & Routine Analysis)
Analytical HPLC and UHPLC systems are the backbone of modern laboratories, offering precise, repeatable measurements for qualitative and quantitative analysis.
System Capabilities
- High-pressure UHPLC operation for fast separations and superior resolution
- Excellent retention time stability and reproducibility
- Flexible modular configurations for evolving laboratory needs
- Seamless integration with UV, DAD, FLD, CAD, ELSD, and MS detectors
Typical System Types & Model Classes
Standard Analytical HPLC Systems
- Ideal for routine QC testing and method transfer
- Flow rates up to ~10 mL/min
- Pressure ranges suitable for conventional columns
UHPLC Systems
- Ultra-high pressure capabilities (up to 1,200–1,500 bar, depending on configuration)
- Designed for sub-2 µm particle columns
- Faster run times and reduced solvent consumption
Integrated LC Platforms
- Binary or quaternary pump systems
- Autosamplers with temperature control
- Column ovens for precise thermal management
Applications
- Pharmaceutical QC and stability testing
- Impurity and degradation profiling
- Food and beverage analysis
- Environmental contaminant testing
- Chemical and materials research
Preparative HPLC Systems
(Compound Purification & Scale-Up)
Preparative HPLC systems are designed for isolating, purifying, and collecting target compounds at milligram to gram scale, while maintaining high purity and recovery.
System Capabilities
- High-flow-rate pumps for larger column diameters
- Automated fraction collection
- Scalable methods from analytical to preparative workflows
- Robust design for continuous operation
Typical System Types & Model Classes
Semi-Preparative HPLC Systems
- Ideal for method development and small-scale purification
- Flow rates typically up to 50–100 mL/min
- Used in pharmaceutical R&D and academic research
Preparative HPLC Systems
- Designed for higher sample loading and throughput
- Supports large-bore columns
- Integrated UV/DAD detection for fraction triggering
Modular Preparative Platforms
- Custom-configurable pumps, detectors, and collectors
- Suitable for pilot-scale production and process development
Applications
- Active pharmaceutical ingredient (API) purification
- Natural product isolation
- Impurity reference standard preparation
- Chemical synthesis and reaction cleanup
Bio-Inert & Biocompatible LC Systems
(Proteins, Peptides & Biologics)
Bio-inert and biocompatible LC systems are engineered specifically for sensitive biomolecules, minimizing adsorption, corrosion, and sample loss.
System Capabilities
- Metal-free or bio-inert flow paths
- Biocompatible materials resistant to salts and aggressive buffers
- Low carryover and high recovery for fragile biomolecules
- Compatibility with native and denaturing conditions
Typical System Types & Model Classes
Bio-Inert UHPLC Systems
- Designed for high-resolution separation of peptides and proteins
- Ideal for coupling with mass spectrometry
Biocompatible HPLC Systems
- Suitable for high-salt mobile phases and buffered systems
- Supports SEC, IEX, and affinity chromatography
Advanced Bio-LC Platforms
- Temperature-controlled autosamplers for sample stability
- Precision flow control at low flow rates
- Optimized for compliance with biopharmaceutical workflows
Applications
- Monoclonal antibody (mAb) characterization
- Peptide mapping and protein profiling
- Biopharmaceutical QC and release testing
- Biomolecule stability and aggregation studies
Detector Compatibility & System Integration
All Chemplanet LC systems are compatible with a wide range of detectors, including:
This ensures flexibility across applications and future-proof system expansion.
End-to-End Support & Compliance
Chemplanet provides complete lifecycle support for liquid chromatography systems:
- Application assessment and system selection
- Professional installation and commissioning
- IQ/OQ/PQ validation support
- Method transfer and optimization
- Preventive maintenance and service contracts
Why Choose Chemplanet for Liquid Chromatography?
- Deep expertise across analytical, preparative, and bio-LC platforms
- Solutions aligned with global laboratory standards
- ISO-aware validation and compliance support
- Rapid technical response across South Africa and SADC
- Long-term partnership approach
Ready to Transform Your LC Capabilities?
Contact our chromatography specialists for a personalized consultation and system demonstration.